Momordica charantia karela commonly known as bitter gourd. Antihyperglycemic and antihyperlipidemic activity of. Endophytic bacteria are known to reside within host plant tissue without giving a harmfull effect. The cassia auriculata herb has been traditionally used in india for medicinal purposes to treat hyperglycemia, diabetes, rheumatism, asthma, and skin diseases. Hypolipidemic agents, or antihyperlipidemic agents, are a diverse group of pharmaceuticals that are used in the treatment of high levels of fats lipids, such as cholesterol, in the blood hyperlipidemia. Plants have a great potential for producing new drugsand used in traditional medicine to treat chronic and even infectious diseases. D i a b e tes o f t l ab n r u o siol journal of diabetes. Antihyperlipidemic activity of the medicinal plants among kadazan. A medicinal plant, galega officinalis led to the discovery and synthesis of metformin.
Frontiers antihyperglycemic and antihyperlipidemic effects. Pdf hyperlipidemia is the greatest hazard factor of coronary heart disease. Hypoglycemic and antihyperlipidemic effect of four korean. Consequently, research is meant to conventional medicinal plants which are used as a part of practices and also the discovery. Antihyperlipidemic activity of the medicinal plants among kadazan and dusun communities in sabah, malaysia. Plantbased medicinal products have been known to man since ancient times, subbulakshmi and naik, 2001.
Plants have played a major role in the introduction of new therapeutic agents. This study was conducted to determine the essential oil percentage of three natural gums of three medicinal plant, commiphora molmol myrrh, boswellia serrata indian frankincense and aloe vera true aloe with evaluation of the antihyperledemic activity of the extracts of the three plants in rats. Paper open access phytochemical screening and antioxidant. Pdf antihyperlipidemic activity of the medicinal plants. Antidiabetic and antihyperlipidemic activity of euphorbia. The present study was carried out to evaluate antidiabetic and antihyperlipidemic effects of dillenia indica methanolic leaves extracts in streptozotocin induced diabetic wistar rats by administering graded oral doses 250 and 500 mgkg body weight for 21 days. Hyperlipidemia is one of the greatest risk factor contributing to. Traditionally, leaves extract of guazuma ulmifolia, psidium guajava, or the rhizome of curcuma xanthorrhiza can. Indian medicinal plants for which antihyperlipidemic activity has not been. Pdf antihyperlipidemic effect of some medicinal plants. Antihyperglycemic activity of aqueous extracts of some medicinal plants on wistar rats ajay kumar sharma and ritika gupta. Antidiabetic and antihyperlipidemic activity of euphorbia thymifolia l. Antihyperlipidemic activities of isolated bio compounds of.
The endophytes may play an important role, as they may produce similar bioactive compounds as produced by the host plant. Mar 14, 2015 medicinal plants with potential antiarthritic activity manjusha choudhary, 1 vipin kumar, 2 hitesh malhotra, 1 and surender singh 3 1 department of pharmacology, institute of pharmaceutical sciences, kurukshetra university, kurukshetra, haryana, india. Antihyperlipidemic effect of some medicinal plants used in bangladeshi traditional medicine. Results of antihyperlipidemic activity groups total cholesterol mgdl mean sem triglyceride.
The antihyperlipidemic activity of the traditional medicinal plants in these. In the present study, the whole methanolic extract of garcinia indica exhibited a significant antihyperlipidemic activity in cholesterol induced hyperlipidemic model in albino wistar rats which was better than that observed with standard drug lovastatin. D i a b e tes o f t l ab n r u o siol journal of diabetes and. The antihyperlipidemic activity of the traditional medicinal plants in these communities is more helpful for the development of new drugs used in the protection against dyslipidemia or atherosclerosis. Antihyperglycemic activity of aqueous extracts of some medicinal plants on wistar rats ajay kumar sharma and ritika gupta department of biotechnology, meerut institute of engineering and technology, miet, meerut, india. Phytochemical screening, antihyperglycemic and antihyperlipidemic effects of aqueous extracts of l. Triton wr39, a nonionic detergent oxy ethylated tertiary octyl phenol formaldehyde polymer can causes acute hyperlipidemia. Hypolipidemic drugs are extensively used to prevent such disorders, but these drugs have other adverse effects. Pdf antihyperlipidemic activity of paeonia anomala l. Antioxidant and antihyperlipidemic activity of hibiscus. Antidiabetic and antihyperlipidemic activities of the leaf. The leaf latex extract of aloe megalacantha has been used for the management of diabetes mellitus in ethiopian folk. Ethanolic extracts of pongamia pinnata fruits, tinospora cordifolia stems, ficus bengalensis aerial.
The leaf latex extract of aloe megalacantha has been used for the management of diabetes mellitus in ethiopian folk medicine. The combination of an hmg coa reductase inhibitor with a bile acidbinding agent has been shown to. Antioxidant and antihyperlipidemic activity of hibiscus sabdariffa linn. Hyperlipidemia hyperlipoproteinemia, is the condition of abnormally elevated levels of any or all lipids andor lipoproteins in the blood.
Therefore searching herbal product with antidiabetic activity possessing fewer side effects receives considerable publicity and provides an opportunity to cure this disease. The extract showed significant antidiabetic activity p medicinal tree that is native to south. Euphorbia after treatment with et extracts fasting blood glucose, hba1c levels, urea. Review medicinal plants with antiarticle inflammatory. The effect of the extracts on diabetesinduced hyperlipidemia has also been studied. In the present study, ethanolic extract of cassia auriculata flower etcaf depicted antihyperlipidemic effect in the budding yeast cells. Hypolipidemic activity, traditional medicine, herbal medicine. Antihyperglycemic activity of compounds isolated from. Antidiabetic and antihyperlipidemic activity of alcoholic. Search for new antidiabetic drugs with minimal or no side effects from medicinal plants is a challenge according to who recommendations. Herbal treatment for hyperlipidemia has no side effects and is relatively contemptible and locally available. Scientific evaluation of medicinal plants according to their ethnopharmacological or traditional methods of use in for treatment of various diseases enables them to be used in modern medicine. The present study was, therefore, undertaken to study the m.
The inadequacies, as well as serious adverse effects associated with conventional medicines, led to a determined search for alternative natural therapeutic agents. Antihyperlipidemic activity of caesalpinia bonducella seeds in hyperglycemic conditions 241. Antihyperlipidemic effect of active principle isolated from. Research article antihyperlipidemic activity of three natural. Simultaneous administration of cinnamomum tamala nees. Antihyperlipidemic activity of cassia auriculata flower. The information is recorded in plant scientific name, family, part used, route of administration, dose given, method used pharmacological method and references. The hyperlipidemic conditions were induced in the yeast cells with oleic acid which showed an. The available drugs for diabetes, insulin or oral hypoglycemic agents have one or more side effects. Antihyperlipidemic drugs for a complete listing of the drugs. The present study was designed to investigate the hypolipidemic effect of cinnamomum tamala nees. Introduction plants have been one of the important sources of medicines since the down of human civilization and still remain one of the major sources of drugs in modern as well as in traditional systems of medicine.
Mar, 2016 75% phospholipids 20%cholesterol 5%glycolipids. Antioxidant and hypolipidemic activity of the hydroethanolic extract. Medicinal plants are the backbone of traditional medicine so considered as good source of life for all people due to its wealthy therapeutic properties and being 100% natural. To consider potentially new hypoglycemic and antihyperlipidemic sources, aqueous extracts. Diabetes mellitus has become a major public health and economic problem across the globe. The activity was observed in a dose dependent manner for all the treated groups. Antihyperlipidemic activity of salacia chinensis root extracts in triton. Type i hyperlipidemia is quite uncommon it is also called familial hyperchylomicronemia and buergergruetz syndrome. Results of antihyperlipidemic activity the antihyperlipidemic activity of the solanum spirale roxb. Caesalpinia bonducella seeds have been used in folklore medicine since ancient times. In vitro antioxidant and antihyperlipidemic activities of.
Biological action of the medicinal plants is related to active chemical constituents alkaloids, flavonoids, polyphenols, tannins, triterpenoids, coumarins, and glycosides usually extending positive effects, because the medicinal properties of plants are due to those chemical constituents 57. In continuation of our search for plantderived antihypercholesterolemic and hypolipidemic agents, we directed our attention to some indian medicinal plants for. Three types of antihyperlipidemic drugs are currently in use, as well as one miscellaneous antihyperlipidemic drug see summary drug table. Several antihyperlipidemic agents are currently available.
Thus, there is an increasing search for the lipid lowering agents from natural origin. Triton wr39 induced hyperlipidemia acute model this model is widely used in order to screen natural or synthetic drugs. The article is undertaken to investigate the herbal plants for. Antihyperlipidemic activity of pongamia pinnata leaf extracts. Plants are known to be the source of many chemical compounds. Adverse effects and reactions allergies and toxicity 243. Evaluation of phytochemical and invivo antihyperlipidemic.
Antihyperlipidemic activity of the medicinal plants among. A rizwan khan1,kaab e alam1,abid hussain abrar1, 1 pharmacology research lab,anwarul uloom college of pharmacy, new mallepally, hyderabad 500016, telangana, india. Antihyperlipidaemic activity of spermacoce hispida. The indian traditional scriptures as well as the ayurvedic texts have. The medicinal plants have been used in traditional medicines for hundreds of years with reputation as efficacious remedies although there may not sufficient scientific data to substantiate their efficacy. The article is undertaken to investigate the herbal plants for antihyperlipidemic activity and models use in this investigation. Pdf antihyperlipidemic effect of some medicinal plants used in. South asian countries have a high prevalence of hyperlipidemia in line with their economic development. Chapter 28 antidiabetic and antihyperlipidemic activity of bonducella caesalpinia bonducella seeds. The aim of this study has been to investigate the possible antihyperlipidemic effect of salacia chinensis root extract in triton 400mgkg b. World journal of pharmacy and pharmaceutical sciences 43. In the early1900s, 80% of all medicines were obtained from roots, barks and leaves. In this aspect, the present study was undertaken to evaluate the antihyperglycemic and antihyperlipidemic effects of piper longum root aqueous extract plraqe.
It is popularly known as guava family myrtaceae and has been used traditionally as a medicinal plant throughout the world for a number of ailments. Bauhinia purpurea is a species of flowering plant in the family fabaceae, native to south china which includes hong kong and southeastern asia. Antidiabetic and antihyperlipidemic activity of alcoholic and. Evaluation of the antihyperlipidemic activity of nelumbo. Plants have been the primary source of drugs and many of the currently available drugs have been directly or indirectly derived from plants. Antidiabetic and antihyperlipidemic effects of dillenia. Naikwade department of pharmacology, appasaheb birnale college of pharmacy, south shivajinagar, sangli416416. In the united states of america, the tree grows in hawaii, coastal california, southern texas, and southwest florida. Research article antihyperlipidemic activity of three. The results from this study contributes to the deeping understanding regarding the potency of endophytic bacteria from medicinal plants which has antihyperlipidemic activity. Balaraman1 1department of pharmacy, sumandeep vidyapeeth, piparia, waghodia, vadodara, gujarat, india391760.
Clerodendrum minahassae,antioxidant, antihyperlipidemic, antiatherosclerotic 1. Antidiabetic and antihyperlipidemic activity of piper longum. The medicinal plants have been used in traditional medicines for hundreds of years with reputation as efficacious remedies although there. Lipase activity of endophytic actinobacteria from medicinal. A comparison was also made between the action of salacia chinensis root extract and a known antihyperlipidemic drug simvastatin 10 mgkg body wt. Thus, plants have been described as an alternative to the development of new drugs 6 applied to treatment of many diseases such as. Aqueous and ethanolic extracts of leaves of cinnamomum tamala nees. Results we have investigated eleven indian medicinal plants for their antihyperglycemic activity table 1. Antihyperlipidemic effect of active principle isolated. Frontiers antihyperglycemic and antihyperlipidemic. Thats why more people are switching towards safer alternatives, specially derived from plants with fewer side effects. We report herein the findings of this research work. Medicinal plants are an important source to treat hyperlipidemia and reduce the risk of certain diseases like atherosclerotic heart disease, heart attack, and heart stroke, but atherosclerosis is the primary cause of death.
Our results demonstrated that chloroform and alcoholic extract of salacia chinensis roots possessed significant antihyperlipidemic activity and hence it could be a potential herbal medicine as adjuvant with existing therapy for the treatment of hyperlipidemia. Recently use of herbal therapies and diet rich in flavonoids and vitamins has augmented significantly to manage minor to modest illnesses. Antidiabetic and antihyperlipidemic activities of the leaf latex extract of aloe megalacantha baker. In india about 150 medicinal plants have been used as herbal drugs against these disorders.
Pdf antihyperlipidemic effect of some medicinal plants used. Ethnobotany is a branch of science which deals with the medicinal plants and their biological activities. There are many synthetic antihyperlipidemic drugs in use. Antidiabetic and antihyperlipidemic activity of piper. Materials and methods plant pharmacological studies have acknowledged the value of medicinal plants as potential source of bioactive compounds. Phenolic compounds present in medicinal plants have been reported to posses powerful antioxidant activity. Pdf internationaljournalofmedicinalplants international.
Antidiabetic and antihyperlipidemic activity of bonducella. Medicinal plants with potential antiarthritic activity manjusha choudhary, 1 vipin kumar, 2 hitesh malhotra, 1 and surender singh 3 1 department of pharmacology, institute of pharmaceutical sciences, kurukshetra university, kurukshetra, haryana, india. Medicinal plants with potential antiarthritic activity. Various medicinal plants have long been used to cure diseases.
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